omics + data science = cures

What drives discoveries?

Data.

We’re here to collect it.

We’re here to make sense of it.

Mass spectrometry-based proteomics, metabolomics and lipidomics, or multi-omics, combined with electronic health records, have the potential to change our health care system for the better.

We envision a focus on prevention using complex models to accurately determine your personal risk of disease.

Now Hiring: Postdoc

Recent Publications

Quantitative Shotgun Proteome Analysis by Direct Infusion

Nature Methods 2020

We need faster methods for omic data collection. This paper describes the first method for shotgun proteomics without liquid chromatography.

Peptide Correlation Analysis (PeCorA) Reveals Differential Proteoform Regulation

Journal of Proteome Research 2020

Proteins exist in multiple forms due to alternative splicing and post-translational modifications. Bottom-up proteomics experiments typically lose the ability to differentiate the original proteoform. This paper describes a computation strategy to recover proteoform differences.

CsoDIA Software for Direct Infusion Shotgun Proteome Analysis

Analytical Chemistry 2021

We describe an automated tool for spectra-spectra matching to enable easy DISPA data analysis. The tool incorporates several algorithmic advances for spectra-spectra matching.